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Article

APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication.

Journal of virology - 1 May 2016

Krisko John F, Begum Nurjahan, Baker Caroline E, Foster John L, Garcia J Victor

Abstract excerpt

UNLABELLED: The multifunctional HIV-1 accessory protein Vif counters the antiviral activities of APOBEC3G (A3G) and APOBEC3F (A3F), and some Vifs counter stable alleles of APOBEC3H (A3H). Studies in humanized mice have shown that HIV-1 lacking Vif expression is not viable. Here, we look at the relative contributions of the three APOBEC3s to viral extinction. Inoculation of bone marrow/liver/thymus (BLT) mice with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosine Deaminase

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Share to vif Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 26912618
DOI: 10.1128/JVI.03275-15
PMCID: PMC4836340

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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