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Article

The Cytolethal Distending Toxin Subunit CdtB of Helicobacter Induces a Th17-related and Antimicrobial Signature in Intestinal and Hepatic Cells In Vitro.

The Journal of infectious diseases - 15 Jun 2016

Péré-Védrenne Christelle, Cardinaud Bruno, Varon Christine, Mocan Iulia, Buissonnière Alice, Izotte Julien, Mégraud Francis, Ménard Armelle

Abstract excerpt

Enterohepatic Helicobacter species are associated with several digestive diseases. Helicobacter pullorum is an emerging human foodborne pathogen, and Helicobacter hepaticus is a mouse pathogen; both species are associated with intestinal and/or hepatic diseases. They possess virulence factors, such as cytolethal distending toxin (CDT). Data indicate that CDT may be involved in chronic inflammatory responses, via...

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PMID: 26908757
DOI: 10.1093/infdis/jiw042

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