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Cytolethal Distending Toxin: A Potential Virulence Factor for<i>Helicobacter cinaedi</i>

15 Dec 2003

Abstract excerpt

Although Helicobacter cinaedi is the most commonly reported enterohepatic helicobacter in humans, there are no reports of virulence factors, and little is known about how it infects and causes disease. In this study, H. cinaedi isolates from humans and animals were examined for production of cytolethal distending toxin (Cdt). Cdt causes distention in cells and arrest in the G2/M phase of cell division. It is...

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PMID: 14673770
DOI: 10.1086/379837

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