Article
Helicobacter pullorum cytolethal distending toxin targets vinculin and cortactin and triggers formation of lamellipodia in intestinal epithelial cells.
The Journal of infectious diseases - 15 Feb 2014
Varon Christine, Mocan Iulia, Mihi Belgacem, Péré-Védrenne Christelle, Aboubacar Anriette, Moraté Christine, Oleastro Mónica, Doignon François, Laharie David, Mégraud Francis, Ménard Armelle
Abstract excerpt
Helicobacter pullorum, a bacterium initially isolated from poultry, has been associated with human digestive disorders. However, the factor responsible for its cytopathogenic effects on epithelial cells has not been formally identified. The cytopathogenic alterations induced by several human and avian H. pullorum strains were investigated on human intestinal epithelial cell lines. Moreover, the effects of the...
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