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Helicobacter pyloriCagL Hypervariable Motif: A Global Analysis of Geographical Diversity and Association With Gastric Cancer

10 Feb 2016

Abstract excerpt

Previous studies suggest overrepresentation of particular polymorphisms within the Helicobacter pylori CagL hypervariable motif (CagLHM) in gastric cancer-associated isolates. However, these disease correlations were geographically variable and ambiguous. We compared the disease correlation of several hundred geographically diverse CagL sequences and identified 33 CagLHM sequence combinations with disparate...

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PMID: 26908724
DOI: 10.1093/infdis/jiw060

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