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Article

Worldwide Phylogenetic and Clinical Risk Association of the Helicobacter pylori Outer Membrane Gene hopQ.

Helicobacter - 1 Jan 2026

Rubio-Hernández Edson I, Fuentes-Pananá Ezequiel M, Thorell Kaisa, Nasimiyu Yonne, Yeager Meredith, Torres Roberto C, Luo Wen, Wang Difei, Camargo M Constanza, Torres Javier, Muñoz-Ramírez Zilia Y

Abstract excerpt

BACKGROUND: Helicobacter pylori (Hp) infection is the primary risk factor for gastric cancer, yet the consequences of the infection vary by bacterial and host factors. The outer membrane protein HopQ plays a key role in Hp adhesion, but its genetic diversity and clinical implications are unclear. HopQ-CEACAM interaction facilitates the translocation of the cytotoxin-associated gene A (CagA). MATERIALS AND...

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PMID: 42394185
DOI: 10.1111/hel.70145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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