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Article

Helicobacter pylori cagL amino acid polymorphisms and its association with gastroduodenal diseases.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jul 2013

Shukla Sanket Kumar, Prasad Kashi Nath, Tripathi Aparna, Jaiswal Virendra, Khatoon Jahanarah, Ghsohal Uday Chand, Krishnani Narendra, Husain Nuzhat

Abstract excerpt

CagL is a pilus protein of Helicobacter pylori that interacts with host cellular α5β1 integrins through its arginine-glycine-aspartate (RGD) motif, guiding proper positioning of the T4SS and translocation of CagA. Deletion or sequence variations of cagL significantly diminished the ability of H. pylori to induce secretion of IL-8 by the host cell. Therefore, this study was undertaken to investigate the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22941498
DOI: 10.1007/s10120-012-0189-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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