Article
Helicobacter pylori cagL amino acid polymorphisms and its association with gastroduodenal diseases.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jul 2013
Shukla Sanket Kumar, Prasad Kashi Nath, Tripathi Aparna, Jaiswal Virendra, Khatoon Jahanarah, Ghsohal Uday Chand, Krishnani Narendra, Husain Nuzhat
Abstract excerpt
CagL is a pilus protein of Helicobacter pylori that interacts with host cellular α5β1 integrins through its arginine-glycine-aspartate (RGD) motif, guiding proper positioning of the T4SS and translocation of CagA. Deletion or sequence variations of cagL significantly diminished the ability of H....
Topics
- Adult
- Amino Acid Sequence
- Bacterial Proteins
- Dyspepsia
- Endoscopy, Gastrointestinal
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- India
- Male
- Middle Aged
- Peptic Ulcer
- Polymerase Chain Reaction