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Helicobacter pylori cagL amino acid polymorphism D58E59 pave the way toward peptic ulcer disease while N58E59 is associated with gastric cancer in north of Iran.

Microbial pathogenesis - 1 Jun 2017

Cherati Mina Rezaee, Shokri-Shirvani Javad, Karkhah Ahmad, Rajabnia Ramzan, Nouri Hamid Reza

Abstract excerpt

The cagL protein of Helicobacter pylori involving in pathogenesis of gastroduodenal disorders. Therefore, the current study was conducted to determine the cagL amino acid polymorphisms in patients with gastric diseases. One hundred gastric biopsies were collected from gastritis, peptic ulcer (PUD) and gastric cancer (GC) patients and were screened for cagL using polymerase chain reaction (PCR). Also, sequence...

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Identifiers

PMID: 28433795
DOI: 10.1016/j.micpath.2017.04.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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