Article
Whole-exome analysis of metaplastic breast carcinomas with extensive osseous differentiation.
Histopathology - 1 Aug 2020
Beca Francisco, Sebastiao Ana P M, Pareja Fresia, Dessources Kimberly, Lozada John R, Geyer Felipe, Selenica Pier, Zeizafoun Nebras, Wen Hannah Y, Norton Larry, Brogi Edi, Weigelt Britta, Reis-Filho Jorge S
Abstract excerpt
AIMS: Metaplastic breast carcinoma (MBC) is a rare type of triple-negative breast cancer that shows vast histological and genetic heterogeneity. Osseous differentiation can be found in different subtypes of MBC. Whether MBCs with osseous differentiation are underpinned by specific genetic alterations has yet to be defined. The aim of this study was to investigate the repertoire of somatic mutations and copy...
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