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Article

Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates.

Proceedings of the National Academy of Sciences of the United States of America - 5 Apr 2016

Peng Chen, Haller Sherry L, Rahman Masmudur M, McFadden Grant, Rothenburg Stefan

Abstract excerpt

Myxoma virus (MYXV) is a rabbit-specific poxvirus, which is highly virulent in European rabbits. The attenuation of MYXV and the increased resistance of rabbits following the release of MYXV in Australia is one of the best-documented examples of host-pathogen coevolution. To elucidate the molecular mechanisms that contribute to the restriction of MYXV infection to rabbits and MYXV attenuation in the field, we...

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Identifiers

PMID: 26903626
DOI: 10.1073/pnas.1515613113
PMCID: PMC4833222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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