Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells.

Virology - 25 Apr 2007

Barrett John W, Shun Chang Chew, Wang Gen, Werden Steven J, Shao Zhuhong, Barrett Catherine, Gao Xiujuan, Belsito Tara A, Villenevue Danielle, McFadden Grant

Abstract excerpt

The myxoma virus M063R gene product exhibits some sequence similarity to the poxvirus host range gene, C7L, of vaccinia virus. To address the potential host range function of the M063R gene product in rabbits, a deletion mutant of myxoma virus (vMyx63KO) was generated and characterized. vMyx63KO replicated to normal titre levels and produced foci that were indistinguishable from those produced by MV in vitro in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Open Reading Frames

Share to Rabbits

Share to Sequence Alignment

Share to Species Specificity

Share to Virulence

Share to Virus Replication

Source

Identifiers

PMID: 17184804
DOI: 10.1016/j.virol.2006.11.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells.PMID 17184804Read ↗

Myxoma virus M-T7, a secreted homolog of the interferon-gamma receptor, is a critical virulence factor for the development of myxomatosis in European rabbits.Semantic proximity Read ↗

Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbitsSemantic proximity Read ↗

Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factorSemantic proximity Read ↗

Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophagesSemantic proximity Read ↗

Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophagesSemantic proximity Read ↗

Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates.Semantic proximity Read ↗

Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication.Semantic proximity Read ↗

Detection of myxoma viruses encoding a defective M135R gene from clinical cases of myxomatosis; possible implications for the role of the M135R protein as a virulence factorSemantic proximity Read ↗

Comparative Analysis of Poxvirus Orthologues of the Vaccinia Virus E3 Protein: Modulation of Protein Kinase R Activity, Cytokine Responses, and Virus PathogenicitySemantic proximity Read ↗

African Swine Fever Virus Multigene Family 360 and 530 Genes Are Novel Macrophage Host Range DeterminantsSemantic proximity Read ↗

Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant.Semantic proximity Read ↗

Evasion of the Innate Immune Type I Interferon System by Monkeypox VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.