Article
Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.
Blood - 26 May 2016
Roccaro Aldo M, Sacco Antonio, Shi Jiantao, Chiarini Marco, Perilla-Glen Adriana, Manier Salomon, Glavey Siobhan, Aljawai Yosra, Mishima Yuji, Kawano Yawara, Moschetta Michele, Correll Mick, Improgo Ma Reina, Brown Jennifer R, Imberti Luisa, Rossi Giuseppe, Castillo Jorge J, Treon Steven P, Freedman Matthew L, Van Allen Eliezer M, Hide Winston, Hiller Elaine, Rainville Irene, Ghobrial Irene M
Abstract excerpt
Familial aggregation of Waldenström macroglobulinemia (WM) cases, and the clustering of B-cell lymphoproliferative disorders among first-degree relatives of WM patients, has been reported. Nevertheless, the possible contribution of inherited susceptibility to familial WM remains unrevealed. We performed whole exome sequencing on germ line DNA obtained from 4 family members in which coinheritance for WM was...
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