Type 1 diabetes associated autoimmunity.

doi:10.1016/j.autrev.2016.02.017

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Article

Type 1 diabetes associated autoimmunity.

Autoimmunity reviews - 1 Jul 2016

Kahaly George J, Hansen Martin P

Abstract excerpt

Diabetes mellitus is increasing in prevalence worldwide. The economic costs are considerable given the cardiovascular complications and co-morbidities that it may entail. Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the loss of insulin-producing pancreatic β-cells. The pathogenesis of T1D is complex and multifactorial and involves a genetic susceptibility that predisposes to abnormal...

Topics

Animals
Autoimmunity
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Humans
Islets of Langerhans
Mice
Organ Specificity

Source

Open in PubMed

Identifiers

PMID: 26903475
DOI: 10.1016/j.autrev.2016.02.017

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