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Genome-wide analysis in northern Chinese twins identifies twelve new susceptibility loci for pulmonary function.

BMC genomics - 30 Dec 2024

Wang Tong, Wang Weijing, Xu Chunsheng, Tian Xiaocao, Zhang Dongfeng

Abstract excerpt

BACKGROUND: Previous genome-wide association studies (GWAS) have established association between genetic variants and pulmonary function across various ethnics, whereas such associations are scarcely reported in Chinese adults. Therefore, we conducted an GWAS to explore relationships between genetic variants and pulmonary function among middle-aged Chinese dizygotic twins and further validated the top variants...

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PMID: 39736507
DOI: 10.1186/s12864-024-11165-6
PMCID: PMC11684132

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