Article
The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer.
Biochimica et biophysica acta. Reviews on cancer - 1 Dec 2017
Terracciano Daniela, Terreri Sara, de Nigris Filomena, Costa Valerio, Calin George A, Cimmino Amelia
Abstract excerpt
Ultraconserved regions (UCRs) represent a relatively new class of non-coding genomic sequences highly conserved between human, rat and mouse genomes. These regions can reside within exons of protein-coding genes, despite the vast majority of them localizes within introns or intergenic regions. Several studies have undoubtedly demonstrated that most of these regions are actively transcribed in normal...
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