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Article

Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling.

Journal of the American Academy of Dermatology - 1 Mar 2016

Soura Efthymia, Eliades Philip J, Shannon Kristen, Stratigos Alexander J, Tsao Hensin

Abstract excerpt

Recent advances in cancer genomics have enabled the discovery of many cancer-predisposing genes that are being used to classify new familial melanoma/cancer syndromes. In addition to CDKN2A and CDK4, germline variants in TERT, MITF, and BAP1 have been added to the list of genes harboring melanoma-predisposing mutations. These newer entities may have escaped earlier description in part because of more advanced...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26892651
DOI: 10.1016/j.jaad.2015.08.037
PMCID: PMC4761106

Genes

BAP1
CDK4
MITF
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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