Article
Genetic risk factors in melanoma etiopathogenesis and the role of genetic counseling: A concise review.
Bosnian journal of basic medical sciences - 16 Sept 2022
Serman Nikola, Vranic Semir, Glibo Mislav, Serman Ljiljana, Bukvic Mokos Zrinka
Abstract excerpt
Melanoma is a highly aggressive cancer originating from melanocytes. Its etiopathogenesis is strongly related to genetic, epigenetic, and environmental factors. Melanomas encountered in clinical practice are predominantly sporadic, whereas hereditary melanomas account for approximately 10% of the cases. Hereditary melanomas mainly develop due to mutations in the CDKN2A gene, which encodes two tumor suppressor...
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