Article
Early developmental gene enhancers affect subcortical volumes in the adult human brain.
Human brain mapping - 1 May 2016
Becker Martin, Guadalupe Tulio, Franke Barbara, Hibar Derrek P, Renteria Miguel E, Stein Jason L, Thompson Paul M, Francks Clyde, Vernes Sonja C, Fisher Simon E
Abstract excerpt
Genome-wide association screens aim to identify common genetic variants contributing to the phenotypic variability of complex traits, such as human height or brain morphology. The identified genetic variants are mostly within noncoding genomic regions and the biology of the genotype-phenotype association typically remains unclear. In this article, we propose a complementary targeted strategy to reveal the genetic...
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