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Article

Genetic variations within human gained enhancer elements affect human brain sulcal morphology.

NeuroImage - 1 Jan 2023

Lemaitre Herve, Le Guen Yann, Tilot Amanda K, Stein Jason L, Philippe Cathy, Mangin Jean-François, Fisher Simon E, Frouin Vincent

Abstract excerpt

The expansion of the cerebral cortex is one of the most distinctive changes in the evolution of the human brain. Cortical expansion and related increases in cortical folding may have contributed to emergence of our capacities for high-order cognitive abilities. Molecular analysis of humans, archaic hominins, and non-human primates has allowed identification of chromosomal regions showing evolutionary changes at...

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Identifiers

PMID: 36442731
DOI: 10.1016/j.neuroimage.2022.119773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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