Article
Increase in Papillary Thyroid Cancer Incidence Is Accompanied by Changes in the Frequency of the BRAF V600E Mutation: A Single-Institution Study.
Thyroid : official journal of the American Thyroid Association - 1 Apr 2016
Kowalska Aldona, Walczyk Agnieszka, Kowalik Artur, Pałyga Iwona, Trybek Tomasz, Kopczyński Janusz, Kajor Maciej, Chrapek Magdalena, Pięciak Liliana, Chłopek Małgorzata, Góźdź Stanisław, Kamiński Grzegorz
Abstract excerpt
BACKGROUND: Thyroid cancer (TC) has one of the fastest increasing incidences worldwide and primarily involves papillary thyroid cancer (PTC). The BRAF(V600E) mutation is the most common genetic alteration identified in PTC. There are few data concerning an association between the rising incidence of PTC and the increasing prevalence of BRAF-positive cases. Environmental factors such as iodine intake may be...
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