Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modifications in the papillary thyroid cancer gene profile over the last 15 years.

The Journal of clinical endocrinology and metabolism - 1 Sept 2012

Romei Cristina, Fugazzola Laura, Puxeddu Efisio, Frasca Francesco, Viola David, Muzza Marina, Moretti Sonia, Nicolosi Maria Luisa, Giani Carlotta, Cirello Valentina, Avenia Nicola, Rossi Stefania, Vitti Paolo, Pinchera Aldo, Elisei Rossella

Abstract excerpt

BACKGROUND: Evidence for an increased prevalence of BRAF(V600E) mutations has been documented in recent decades. The aim of this study was to evaluate the prevalence of both RET/PTC rearrangements and BRAF(V600E) mutations in an Italian cohort of papillary thyroid carcinoma (PTC) patients followe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary
Share to DNA Fingerprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Neoplasm Metastasis

Share to Proto-Oncogene Proteins c-ret

Share to Sicily

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 22745248
DOI: 10.1210/jc.2012-1269

Genes

BRAF
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22745248-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modifications in the papillary thyroid cancer gene profile over the last 15 years.PMID 22745248Read ↗

The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review.Semantic proximity Read ↗

Increase in Papillary Thyroid Cancer Incidence Is Accompanied by Changes in the Frequency of the BRAF V600E Mutation: A Single-Institution Study.Semantic proximity Read ↗

The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations.Semantic proximity Read ↗

A Shift in Molecular Drivers of Papillary Thyroid Carcinoma Following the 2017 World Health Organization Classification: Characterization of 554 Consecutive Tumors With Emphasis on BRAF-Negative Cases.Semantic proximity Read ↗

Higher rate of BRAF mutation in papillary thyroid cancer over time: a single-institution study.Semantic proximity Read ↗

High prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas: correlation with more aggressive phenotype and decreased expression of iodide-metabolizing genes.Semantic proximity Read ↗

Clinical significance of BRAF mutation in thyroid papillary cancer.Semantic proximity Read ↗

Correlation between gene mutations and clinical characteristics in papillary thyroid cancer: a retrospective analysis of BRAF mutations and RET rearrangementsSemantic proximity Read ↗

BRAFV600E mutation in the pathogenesis of a large series of papillary thyroid carcinoma in Czech Republic.Semantic proximity Read ↗

Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns)).Semantic proximity Read ↗

BRAF mutations in an Italian cohort of thyroid cancers.Semantic proximity Read ↗

Oncogenic alterations in papillary thyroid cancers of young patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.