Article
BRAF and KRAS mutations in papillary thyroid carcinoma in the United Arab Emirates.
PloS one - 1 Jan 2020
Al-Salam Suhail, Sharma Charu, Afandi Bachar, Al Dahmani Khaled, Al-Zahrani Ali S, Al Shamsi Amal, Al Kaabi Juma
Abstract excerpt
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common malignant thyroid neoplasm comprising 80-90% of all thyroid malignancies. Molecular changes in thyroid follicular cells are likely associated with the development of PTC. Mutations in serine/threonine-protein kinase (BRAF) and Rat sarcoma viral oncogene homolog (RAS) are commonly seen in PTC. METHODS: In total, 90 cases of PTC are randomly selected...
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