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Article

NFE2L2 variations reduce antioxidant response in patients with Parkinson disease.

Oncotarget - 8 Mar 2016

Gui YaXing, Zhang LiShan, Lv Wen, Zhang WenMing, Zhao JinJia, Hu XingYue

Abstract excerpt

Oxidative stress has been recognized as a risk factor of Parkinson's disease (PD) development. We hypothesized that decreased function of the nuclear factor (erythroid-derived 2)-like 2 (NFE2L2)-antioxidant response element (ARE) pathway might predispose to Parkinsonism. A case-control study was performed between NFE2L2 Single Nucleotide Polymorphism (SNP) and PD in a cohort of 765 unrelated patients with...

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Identifiers

PMID: 26887053
DOI: 10.18632/oncotarget.7353
PMCID: PMC4905436

Genes

GSTM1
GSTP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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