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Article

Genetic alterations of prostate cancer: in localized and metastatic prostate cancer.

BMC urology - 14 Jul 2025

Yoon Chang Eil, Kang San, Rhew Seung Ah, Kwon Hyeok Jae, Shin Dongho, Moon Hyong Woo, Kim Mee Young, Lee Ji Youl

Abstract excerpt

PURPOSE: The purpose of this study was to identify genetic mutations in patients with localized and metastatic prostate cancer, exploring the relationship between these mutations and clinical outcomes. MATERIALS AND METHODS: We conducted next-generation sequencing on tissue samples from 106 prostate cancer patients at Seoul St. Mary’s Hospital, analyzing prostate-specific antigen (PSA) levels, tumor, node,...

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Identifiers

PMID: 40660132
DOI: 10.1186/s12894-025-01840-5
PMCID: PMC12257693

Genes

BCR
BRCA2
LRP6
PIK3CA
APOBEC3B
BCL6
CHEK2
ERG
TMPRSS2

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