Article
Germline variant screening with targeted next generation sequencing in prostate cancer: phenotype-genotype correlation.
Turkish journal of medical sciences - 1 Feb 2022
Çakır Ali Yavuz, Hekimler Öztürk Kuyaş, Özorak Alper
Abstract excerpt
BACKGROUND: Next generation sequencing provides new information about the molecular pathogenesis of cancer. We used a targeted NGS-based multiple gene panel comprising prostate cancer (PCa) predisposing genes to assess the prevalence of germline mutations in PCa patients. METHODS: In a cohort of twenty-one PCa patients with a family history of cancer, a targeted multigene panel consisting of 39 genes associated...
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