Article
Tripartite motif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22.
Journal of hypertension - 1 May 2016
Prestes Priscilla R, Marques Francine Z, Lopez-Campos Guillermo, Booth Scott A, McGlynn Maree, Lewandowski Paul, Delbridge Lea M D, Harrap Stephen B, Charchar Fadi J
Abstract excerpt
BACKGROUND: Left ventricular (LV) hypertrophy is a risk factor for cardiovascular death, but the genetic factors determining LV size and predisposition to hypertrophy are not well understood. We have previously linked the quantitative trait locus cardiac mass 22 (Cm22) on chromosome 2 with cardiac hypertrophy independent of blood pressure in the spontaneously hypertensive rat. From an original cross of...
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