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Article

Genetic and functional implications of an exonic TRIM55 variant in heart failure.

Journal of molecular and cellular cardiology - 1 Jan 2020

Heliste Juho, Chheda Himanshu, Paatero Ilkka, Salminen Tiina A, Akimov Yevhen, Paavola Jere, Elenius Klaus, Aittokallio Tero

Abstract excerpt

BACKGROUND: To tackle the missing heritability of sporadic heart failure, we screened for novel heart failure-associated genetic variants in the Finnish population and functionally characterized a novel variant in vitro and in vivo. METHODS AND RESULTS: Heart failure-associated variants were screened in genotyping array data of the FINRISK study, consisting of 994 cases and 20,118 controls. Based on logistic...

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Identifiers

PMID: 31866377
DOI: 10.1016/j.yjmcc.2019.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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