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Article

MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress

23 Mar 2013

Abstract excerpt

RATIONALE: The adult heart is composed primarily of terminally differentiated, mature cardiomyocytes that express signature genes related to contraction. In response to mechanical or pathological stress, the heart undergoes hypertrophic growth, a process defined as an increase in cardiomyocyte cell size without an increase in cell number. However, the molecular mechanism of cardiac hypertrophy is not fully...

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Share to Cardiac Fibrosis and Remodeling
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PMID: 23524588
DOI: 10.1161/circresaha.112.300682

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