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Article

Anti-fibrotic characteristics of Vγ9+ γδ T cells in systemic sclerosis.

Clinical and experimental rheumatology - 1 Jan 2000

Markovits Noa, Bendersky Anna, Loebstein Ronen, Brusel Marina, Kessler Efrat, Bank Ilan

Abstract excerpt

OBJECTIVES: γδ T cells of the Vγ9Vδ2 subtype secrete anti-fibrotic cytokines upon isopentenyl pyrophosphate (IPP) stimulation. In this study, we sought to compare IPP and Zoledronate, an up-regulator of IPP, effects on proliferation and cytokine secretion of Vγ9+ T cells from systemic sclerosis (SSc) patients and healthy controls (HCs). We also examined the effect of IPP-triggered peripheral blood mononuclear...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell, gamma-delta

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Source

Identifiers

PMID: 26886502

Genes

IPP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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