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Article

Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts.

Rheumatology (Oxford, England) - 1 Feb 2010

Shi-wen Xu, Eastwood Mark, Stratton Richard J, Denton Christopher P, Leask Andrew, Abraham David J

Abstract excerpt

OBJECTIVE: The transcription factor peroxisome proliferator-activated receptor (PPAR)-gamma plays an important role in controlling cell differentiation. The aim of the present study was to examine whether PPAR-gamma expression was reduced in skin scleroderma fibroblasts and whether PPAR-gamma ago...

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Identifiers

PMID: 20007285
DOI: 10.1093/rheumatology/kep371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20007285-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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