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Article

The CodY regulator is essential for virulence in Streptococcus suis serotype 2.

Scientific reports - 17 Feb 2016

Feng Liping, Zhu Jiawen, Chang Haitao, Gao Xiaoping, Gao Cheng, Wei Xiaofeng, Yuan Fangyan, Bei Weicheng

Abstract excerpt

The main role of CodY, a global regulatory protein in most low G + C gram-positive bacteria, is in transcriptional repression. To study the functions of CodY in Streptococcus suis serotype 2 (S. suis 2), a mutant codY clone named ∆codY was constructed to explore the phenotypic variation between ∆codY and the wild-type strain. The result showed that the codY mutation significantly inhibited cell growth, adherence...

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PMID: 26883762
DOI: 10.1038/srep21241
PMCID: PMC4756307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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