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Article

Inactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis.

Virulence - 1 Dec 2020

Ni Hua, Li Min, Wang Qiaoqiao, Wang Jing, Liu Xumiao, Zheng Feng, Hu Dan, Yu Xu, Han Yifang, Zhang Qi, Zhou Tingting, Wang Yiwen, Wang Chunhui, Gao Jimin, Shao Zhu-Qing, Pan Xiuzhen

Abstract excerpt

STREPTOCOCCUS SUIS: serotype 2 (S. suis 2) is an important swine pathogen and also an emerging zoonotic agent. HtpsA has been reported as an immunogenic cell surface protein on the bacterium. In the present study, we constructed an isogenic mutant strain of htpsA, namely ΔhtpsA, to study its role in the development and virulence of S. suis 2. Our results showed that the mutant strain lost its typical encapsulated...

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Identifiers

PMID: 32815473
DOI: 10.1080/21505594.2020.1792080
PMCID: PMC7567435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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