Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypically Adapted Mycobacterium tuberculosis Populations from Sputum Are Tolerant to First-Line Drugs.

Antimicrobial agents and chemotherapy - 1 Apr 2016

Turapov Obolbek, O'Connor Benjamin D, Sarybaeva Asel A, Williams Caroline, Patel Hemu, Kadyrov Abdullaat S, Sarybaev Akpay S, Woltmann Gerrit, Barer Michael R, Mukamolova Galina V

Abstract excerpt

Tuberculous sputum contains multipleMycobacterium tuberculosispopulations with different requirements for isolationin vitro These include cells that form colonies on solid media (plateableM. tuberculosis), cells requiring standard liquid medium for growth (nonplateableM. tuberculosis), and cells requiring supplementation of liquid medium with culture supernatant (SN) for growth (SN-dependentM. tuberculosis)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Biological Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cryopreservation

Share to Isoniazid

Share to Multilocus Sequence Typing

Share to Sputum

Share to Streptomycin

Share to Tuberculosis, Pulmonary

Source

Open in PubMed Open full text

Identifiers

PMID: 26883695
DOI: 10.1128/AAC.01380-15
PMCID: PMC4808147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypically Adapted Mycobacterium tuberculosis Populations from Sputum Are Tolerant to First-Line Drugs.PMID 26883695Read ↗

Targeting Phenotypically Tolerant Mycobacterium tuberculosisSemantic proximity Read ↗

Transcriptional Adaptation of Drug-tolerantMycobacterium tuberculosisDuring Treatment of Human TuberculosisSemantic proximity Read ↗

Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.Semantic proximity Read ↗

Drug-induced differential culturability in diverse strains of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

A method for the enrichment, isolation and validation of Mycobacterium smegmatis population surviving in the presence of bactericidal concentrations of rifampicin and moxifloxacinSemantic proximity Read ↗

Assessing the propensity of TB clinical isolates to form viable but non-replicating subpopulations.Semantic proximity Read ↗

Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with TuberculosisSemantic proximity Read ↗

Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosisSemantic proximity Read ↗

Origin and dynamics of <i>Mycobacterium tuberculosis</i> subpopulations that predictably generate drug tolerance and resistanceSemantic proximity Read ↗

Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosisSemantic proximity Read ↗

Phase variation in <i>Mycobacterium tuberculosis glpK</i> produces transiently heritable drug toleranceSemantic proximity Read ↗

A modified decontamination and storage method for sputum from patients with tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.