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Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with Tuberculosis

7 Jul 2016

Abstract excerpt

Abstract Rationale Recent studies suggest that baseline tuberculous sputum comprises a mixture of routinely culturable and differentially culturable tubercle bacteria (DCTB). The latter seems to be drug tolerant and dependent on resuscitation-promoting factors (Rpfs). Objectives To further explore this, we assessed sputum from patients with tuberculosis for DCTB and studied the impact of exogenous culture...

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PMID: 27387272
DOI: 10.1164/rccm.201604-0769oc

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