Article
Liquid biopsy of fine-needle aspiration supernatant for lung cancer genotyping.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2018
Guibert Nicolas, Tsukada Hisashi, Hwang David H, Chambers Emily, Cibas Edmund S, Bale Tejus, Supplee Julianna, Ulrich Bryan, Sholl Lynette M, Paweletz Cloud P, Oxnard Geoffrey R
Abstract excerpt
BACKGROUND: Tumor genotyping is transforming lung cancer care but requires adequate tumor tissue. Advances in minimally invasive biopsy techniques have increased access to difficult-to-access lesions, but often result in smaller samples. With the advent of highly sensitive DNA genotyping methods used for plasma analysis, we hypothesized that these same methods might allow genotyping of free DNA derived from fine...
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