Article
Sequence variants of peroxisome proliferator-activated receptor-gamma gene and the clinical courses of patients with end-stage renal disease.
Disease markers - 1 Jan 2015
Chao Chia-Ter, Chen Yen-Ching, Chiang Chih-Kang, Huang Jenq-Wen, Hu Fu-Chang, Fang Cheng-Chung, Chang Chen-Chih, Yen Chung-Jen
Abstract excerpt
BACKGROUND: PPAR-γ single nucleotide polymorphisms (SNPs) reportedly play an important role in determining metabolic risk among diverse population. Whether PPAR-γ SNPs affect the clinical courses in ESRD patients is unknown. METHODS: From a multicenter cohort, we identified 698 patients with prevalent ESRD between 2002 and 2003, and other 782 healthy subjects as control. Two PPAR-γ SNPs, Pro12Ala (rs1801282) and...
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