Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.

doi:10.1007/s12664-016-0618-3

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Article

Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Jan 2016

Nemr Nader, Kishk Rania, Mandour Mohamed

Abstract excerpt

BACKGROUND: Ribavirin (RBV)-induced anemia is one of the major causes of dose reduction and discontinuation of therapy for chronic hepatitis C (CHC) patients. We investigated the role of inosine triphosphate pyrophosphatase (ITPA) single nucleotide polymorphism (SNP) (rs1127354) in predicting RBV-induced anemia and thrombocytopenia among Egyptian patients with CHC genotype 4 infection. METHODS: One hundred and...

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Identifiers

PMID: 26880169
DOI: 10.1007/s12664-016-0618-3

Genes

ITPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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