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Article

Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.

Journal of gastroenterology - 1 Nov 2012

Kobayashi Tomoe, Hige Shuhei, Terashita Katsumi, Nakai Masato, Horimoto Hiromasa, Sho Takuya, Nakanishi Mitsuru, Ogawa Koji, Chuma Makoto, Sakamoto Naoya, Asaka Masahiro

Abstract excerpt

BACKGROUND: An inosine triphosphatase (ITPA) single-nucleotide polymorphism (SNP) is associated with anemia induced by pegylated interferon and ribavirin (RBV) combination therapy in patients with chronic hepatitis C (CHC). However, there are very few reports on the hematological effects of RBV monotherapy. Here, hematological changes were monitored in patients with CHC who received RBV monotherapy, and the...

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Topics

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Share to Anemia
Share to Erythropoietin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemoglobins

Share to Hepatitis C, Chronic

Share to Platelet Count

Share to Pyrophosphatases

Share to Ribavirin

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Source

Identifiers

PMID: 22460221
DOI: 10.1007/s00535-012-0579-y

Genes

EPO
ITPA
TPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.PMID 22460221Read ↗

Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.Semantic proximity Read ↗

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ITPA gene variation and ribavirin‐induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirinSemantic proximity Read ↗

Inosine triphosphatase polymorphisms and ribavirin pharmacokinetics as determinants of ribavirin-associate anemia in patients receiving standard anti-HCV treatment.Semantic proximity Read ↗

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection.Semantic proximity Read ↗

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Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin.Semantic proximity Read ↗

Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.Semantic proximity Read ↗

Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.Semantic proximity Read ↗

ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.Semantic proximity Read ↗

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