Article
Association between IPTA gene polymorphisms and hematological abnormalities in hepatitis C virus-infected patients receiving combination therapy.
Gut and liver - 1 Mar 2015
Hwang Jow Jyh, Lo Ching Chu, Lin Chien Hung, Cheng Hsu Sheng, Hung I Wen, Tsai Wan Ju, Hung Chien Hui
Abstract excerpt
BACKGROUND/AIMS: Hematological abnormalities during hepatitis C virus (HCV) combination therapy with pegylated interferon α and ribavirin often necessitate dose reduction. Variants of the ITPA gene have been reported to protect against anemia during the early stages of HCV combina-tion treatments but have also been associated with larger decreases in platelet counts. We aimed to identify the as-sociation between...
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