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Article

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.

Scientific reports - 16 Feb 2016

Obaldía Nicanor, Dow Geoffrey S, Gerena Lucia, Kyle Dennis, Otero William, Mantel Pierre-Yves, Baro Nicholas, Daniels Rachel, Mukherjee Angana, Childs Lauren M, Buckee Caroline, Duraisingh Manoj T, Volkman Sarah K, Wirth Dyann F, Marti Matthias

Abstract excerpt

Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies. However, artemisinin resistant parasites have recently emerged in South-East Asia. Novel intervention strategies are therefore urgently needed to maintain the current momentum for control and elimination of this disease. In the present study...

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Identifiers

PMID: 26880111
DOI: 10.1038/srep21216
PMCID: PMC4754742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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