Article
Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2013
Moon Robert W, Hall Joanna, Rangkuti Farania, Ho Yung Shwen, Almond Neil, Mitchell Graham H, Pain Arnab, Holder Anthony A, Blackman Michael J
Abstract excerpt
Research into the aetiological agent of the most widespread form of severe malaria, Plasmodium falciparum, has benefitted enormously from the ability to culture and genetically manipulate blood-stage forms of the parasite in vitro. However, most malaria outside Africa is caused by a distinct Plasmodium species, Plasmodium vivax, and it has become increasingly apparent that zoonotic infection by the closely...
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