Article
Detection EGFR exon 19 status of lung cancer patients by DNA electrochemical biosensor.
Biosensors & bioelectronics - 15 Jun 2016
Xu Xiong-Wei, Weng Xiu-Hua, Wang Chang-Lian, Lin Wei-Wei, Liu Ai-Lin, Chen Wei, Lin Xin-Hua
Abstract excerpt
Epidermal growth factor receptor (EGFR) exon 19 mutation status is a very important prediction index for tyrosine kinase inhibitors (TKIs) therapy. In this paper, we constructed a superior selective sandwich-type electrochemical biosensor to detect in-frame deletions in exon 19 of EGFR in real samples of patients with non-small cell lung carcinoma. Based on the characteristics of different hybridization...
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