Article
Palindromic-assisted self-annealing transcription amplification for reliable genotyping of epidermal growth factor receptor exon mutations.
Biosensors & bioelectronics - 15 Dec 2021
Yuan Rui, Tang Wanyan, Zhang Hong, You Wenxin, Hu Xiaolin, Zhang Haiwei, Chen Ling, Nian Weiqi, Ding Shijia, Luo Yang
Abstract excerpt
Reliable discrimination of specific epidermal growth factor receptor (EGFR) gene mutations plays a critical role in guiding lung cancer therapeutics. Until now, convenient and accurate recognition of the specific deletion of EGFR exons has remained particularly challenging. Herein, we propose a palindromic-assisted self-annealing transcription amplification (PASTA) strategy for the reliable detection of...
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