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Article

OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele.

Monoclonal antibodies in immunodiagnosis and immunotherapy - 1 Feb 2016

Hatherley Deborah, Aknin Marie-Laure, Barclay A Neil

Abstract excerpt

The SIRP family of myeloid-paired receptors are characterized by having both activating and inhibiting members with extracellular regions that are relatively similar. Making good reagents to these receptors is not straightforward, particularly as they are relatively polymorphic. We describe the production of a monoclonal antibody (MAb) called OX130 that recognizes both common alleles of the human activating...

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Identifiers

PMID: 26871367
DOI: 10.1089/mab.2015.0054
PMCID: PMC4770912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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