Article
Associations between a fatty acid desaturase gene polymorphism and blood arachidonic acid compositions in Japanese elderly.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Feb 2016
Horiguchi Sayaka, Nakayama Kazuhiro, Iwamoto Sadahiko, Ishijima Akiko, Minezaki Takayuki, Baba Mamiko, Kontai Yoshiko, Horikawa Chika, Kawashima Hiroshi, Shibata Hiroshi, Kagawa Yasuo, Kawabata Terue
Abstract excerpt
We investigated whether the single nucleotide polymorphism rs174547 (T/C) of the fatty acid desaturase-1 gene, FADS1, is associated with changes in erythrocyte membrane and plasma phospholipid (PL) long-chain polyunsaturated fatty acid (LCPUFA) composition in elderly Japanese participants (n=124; 65 years or older; self-feeding and oral intake). The rs174547 C-allele carriers had significantly lower arachidonic...
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