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Article

Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population.

Prostaglandins, leukotrienes, and essential fatty acids - 1 Sept 2020

Hammouda Souha, Ghzaiel Imen, Khamlaoui Wided, Hammami Sonia, Mhenni Samia Younes, Samet Slim, Hammami Mohamed, Zarrouk Amira

Abstract excerpt

Polyunsaturated fatty acids (PUFAs) are closely related to various physiological conditions. In several age-related diseases including Alzheimer's disease (AD) altered PUFAs metabolism has been reported. However, the mechanism behind PUFAs impairment and AD developpement remains unclear. In humans, PUFAs biosynthesis requires delta-5 desaturase (D5D), delta-6 desaturase (D6D) and elongase 2 activities; which are...

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Source

Identifiers

PMID: 32682282
DOI: 10.1016/j.plefa.2020.102159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population.PMID 32682282Read ↗

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