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The Relationship Between Endothelial Nitric Oxide Synthase Gene (NOS3) Polymorphisms, NOS3 Expression, and Varicocele.

Genetic testing and molecular biomarkers - 1 Apr 2016

Kahraman Cigdem Yuce, Tasdemir Sener, Sahin Ibrahim, Marzioglu Ozdemir Ebru, Yaralı Oguzhan, Ziypak Tevfik, Adanur Senol, Kahraman Mustafa, Tatar Abdulgani

Abstract excerpt

BACKGROUND: Varicocele is an abnormal enlargement of the pampiniform venous plexus in the scrotum. Varicocele is the most common cause of secondary male infertility. Nitric oxide (NO), which has a role on varicocele pathophysiology, is synthesized by endothelial nitric oxide synthase gene (NOS3). OBJECTIVE: In our study, we aimed to explain the relationship between varicocele, three common NOS3 polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26866567
DOI: 10.1089/gtmb.2015.0294

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NOS3

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