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Article

Relation of nitric oxide synthase gene (NOS3) polymorphisms to varicocele risk and post-varicocelectomy seminal oxidative stress reduction.

Andrologia - 1 Apr 2020

Omar Salma Samir, Mahfouz Wally, Dawood Waleed, Abo El-Wafa Reham Abdel Haleem, Ghazala Rasha Abdelmawla, Zahran Abdel-Rahman Mahmoud

Abstract excerpt

The pathophysiology of varicocele remains to be unknown. Several genetic factors have been implicated in varicocele etiopathogenesis. We studied the relationship between NOS3 c.894G>T, c.786T>C and 4b/a polymorphisms to varicocele risk and their prognostic value as regards improvement of the post-operative seminal parameters &/or seminal malonaldehyde levels. The three NOS3 polymorphisms were evaluated in 100...

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PMID: 32022285
DOI: 10.1111/and.13525

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