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Article

NOS3 gene variants and male infertility: Association of 4a/4b with oligoasthenozoospermia.

Andrologia - 1 Feb 2018

Vučić N L J, Nikolić Z Z, Vukotić V D, Tomović S M, Vuković I I, Kanazir S D, Savić-Pavićević D L J, Brajušković G N

Abstract excerpt

Results of recent studies confirmed that oxidative stress negatively affects sperm motility and causes sperm DNA damage. Produced by nitric oxide synthase 3 (NOS3), nitric oxide is considered to be one of the important mediators of oxidative stress in testis tissue. The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene...

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PMID: 28466478
DOI: 10.1111/and.12817

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NOS3

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