Article
Functional Variations in the NOS3 Gene Are Associated With Erectile Dysfunction Susceptibility, Age of Onset and Severity in a Han Chinese Population.
The journal of sexual medicine - 1 Apr 2017
Yang Bo, Liu Liangren, Peng Zhufeng, Lu Dongliang, Ren Zhengju, Liu Shengzuo, Yang Xiling, Liao Jian, Dong Qiang
Abstract excerpt
BACKGROUND: Impaired function of endothelial nitric oxide synthase (eNOS) is involved in the pathologic processes of erectile dysfunction (ED), and three functional polymorphisms (G894T, T-786C, and a tandem repeat of 27 bp in intron 4) in the NOS3 gene, which encodes eNOS, are associated with the clinical characteristics of ED in several populations. AIM: To investigate the effect of these variations of NOS3 on...
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